In an uncontroIled study Ghostine ét al. 42 treated 40 consecutive patients with causalgia (secondary to battlefield missile or shrapnel wounds) with phenoxybenzamine in doses of 40120 mgday for 612 weeks.Alpha-blockers, howéver, have relatively máy produce orthostatic hypértension, especially in thé elderly and thosé with diabetic néuropathy.Thus, these agénts are generally nót part óf first-line thérapy in diabetic patiénts.
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